Medici is located 34 km from Split, 10 km from Omis, 24 km from Makarska and 195 km from Dubrovnik.
There are two possibilities ways of arriving via highway A1:
1. At the exit Split on A1,  follow the signs for Omiš and drive for about 50 km. After passing the town of Omis continue for another 11 km.
2. At the exit Šestanovac on A1, follow the signs for Omis and drive about 20 km.

In addition, you can reach by ferry from Ancona to Split and then by local bus to Medici additional 34 km, and it is also possible to arrive by plane to the airport Resnik, which is 60 km away.